Peptides/BPC-157

For Research Purposes Only. This page summarizes published preclinical and clinical research. It does not constitute medical advice and is not a recommendation for human use. Always consult a qualified healthcare professional.

Tissue Repair

BPC-157

Synthetic pentadecapeptide derived from human gastric juice protein. Studied extensively in preclinical models for tendon, gut, and systemic tissue repair.

Class

Pentadecapeptide

Sequence Length

15 amino acids

Trial Status

Preclinical

FDA Approval

None

Overview

BPC-157 (Body Protective Compound 157) is a synthetic pentadecapeptide consisting of 15 amino acids. Its sequence is derived from a protein found in human gastric juice, where it was first identified in the early 1990s by researchers investigating gastroprotective mechanisms. Unlike many research peptides, BPC-157 demonstrates stability in gastric acid, which has contributed to interest in both local gastrointestinal and systemic applications.

Preclinical research has investigated BPC-157 across a wide range of tissue types and injury models. Studies in rodents have examined effects on tendon-to-bone healing, muscle repair following transection or crush injury, intestinal anastomosis healing, and colitis-model inflammation. The compound appears to act through multiple downstream pathways simultaneously — including upregulation of growth hormone receptor expression on target cells, stimulation of vascular endothelial growth factor (VEGF) and nitric oxide signaling to promote angiogenesis, and modulation of inflammatory cytokine cascades. This multi-pathway activity profile has generated significant research interest, though it also complicates mechanistic interpretation.

The volume of peer-reviewed preclinical literature on BPC-157 is substantial, with over 100 published studies examining its effects across gastrointestinal, musculoskeletal, neurological, and systemic models. Most of this work has been conducted by a single research group (Sikiric et al. at the University of Zagreb), which is a relevant caveat when evaluating the overall evidence base. Independent replication of key findings is limited. As of early 2026, BPC-157 has not advanced to published Phase III human clinical trials, and its mechanism of action in humans has not been confirmed through controlled studies.

Research Status

FDA Status

Not FDA-approved for any indication. No publicly available IND (Investigational New Drug) filing for standard therapeutic use. BPC-157 is classified as a research chemical in the United States.

Trial Phase

Preclinical only. The body of published research consists almost entirely of rodent and in vitro models. No published Phase III human trial data as of early 2026.

Key Studies

Sikiric et al. have published extensively across multiple journals including Current Pharmaceutical Design, Journal of Physiology–Paris, and World Journal of Gastroenterology. A 2018 review in Current Pharmaceutical Design (Sikiric et al.) provides a comprehensive summary of the gastroprotective and systemic repair literature. Independent replication studies are limited.

Common Research Protocols

Dose range (published models)1–10 mcg/kg body weight (animal); 200–500 mcg/day (community-reported)

Administration routes studiedSubcutaneous, intramuscular, intraperitoneal (animal); SC most common in community use

Typical vial sizes available2mg, 5mg

Common forms soldAcetate salt (most common); arginate salt (less common, different solubility)

Reconstitution solventBacteriostatic water (0.9% benzyl alcohol in sterile water)

Typical research run length4–12 weeks

The dose ranges above are extrapolated from animal research and community-reported use. They have not been validated in human clinical trials. This information is for educational reference only and is not a recommendation for human use.

Use the reconstitution calculator →

Storage & Handling

Lyophilized (freeze-dried) BPC-157 should be stored at −20°C before reconstitution. Once reconstituted, store at 4°C (refrigerated) and use within 30 days. Avoid repeated freeze-thaw cycles. Keep away from light.

What to Look for When Buying

Prioritize vendors with independent third-party HPLC testing. Finnrick Analytics tests for both purity and quantity accuracy — a vendor with high purity but severe quantity underfill still delivers less active compound per vial.

Confirm the form: most research BPC-157 is supplied as acetate salt. BPC-157 arginate salt (occasionally sold as "stable BPC-157") has different solubility characteristics and the research literature is based on the acetate form.

A grade-A purity score (≥98% HPLC) is the appropriate baseline for research use. Anything below 95% (C grade or lower) represents significant impurity.

Check whether the vendor tests for quantity accuracy in addition to purity. A vial labeled 5mg that contains 3.5mg active compound is a meaningful discrepancy that HPLC purity tests alone will not catch. Finnrick measures both.

Reputable vendors publish Certificates of Analysis (COAs) with each batch and make them accessible on product pages. COA dates should be recent — ideally within 12 months of purchase.

Compare Vendor Pricing

PepVendors tracks live pricing for BPC-157 across multiple vendors, updated weekly. Compare price per mg, available sizes, and purity data side by side.

Compare BPC-157 prices →

Third-Party Purity Data

Full data at finnrick.com →

Independent HPLC test results from Finnrick Analytics. Purity values are averages across multiple samples. Check the Finnrick vendor page for batch-level detail.

VendorPurity

100.0%A

100.0%A

99.9%A

99.8%A

99.7%A

99.6%A

99.3%A

99.1%A

99.1%A

98.9%A

98.9%A

98.5%A

98.4%A

90.6%C

75.9%D

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Legal Disclaimer

For Research Purposes Only — Not Medical Advice. The information on this page is compiled from published peer-reviewed research, publicly available clinical trial data, and independent third-party testing results. It is intended solely as an educational reference for researchers.

Nothing on this page constitutes medical advice, a diagnosis, or a treatment recommendation. Peptides listed as research chemicals are not approved for human consumption unless explicitly noted as FDA-approved pharmaceuticals. PepVendors is a price comparison and information platform — we do not manufacture, sell, or distribute any compounds. Always consult a qualified and licensed healthcare professional before considering any compound for personal use.